One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing ...

Cancer immunotherapy has proven efficacy in some cancer subtypes but it often fails to deliver clinically meaningful benefits to patients because their tumors are poorly immunogenic. A major goal of ...

Mammalian hearts have almost no ability to grow new heart muscle cells, called cardiomyocytes, after birth. Thus, dead tissue after an adult heart attack is not repaired with new cardiomyocytes. It is ...