The characteristics of tableted solid dosage drugs often depend on the granulation process, so selecting the most appropriate granulation technique and monitoring the process are crucial Granulation ...

Using a specific addition method to wet the powder bed in twin-screw granulation using a foam binder improves robustness for continuous solid-dosage drug product manufacturing. In less than a decade, ...

Formulating drugs to ensure therapeutic consistency, enable rapid development, and allow for cost-effective scale-up has become increasingly challenging. This is especially true in the context of ...

Spatial filter techniques, along with delivering real-time particle size measurement, offer several further attractions such as simple hardware requirements, ease of use and reasonable commercial cost ...

Pharmaceutical manufacturing practices are advancing towards a future in which continuous manufacturing processes will be the norm. Developing and applying such techniques is therefore an essential ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Fluidized bed spray granulation is a versatile process that integrates the controlled spraying of a binder liquid onto fluidized particles, leading to the formation of agglomerates or granules with ...

Granulation and agglomeration technology is a popular topic and of growing interest for different industries - and, therefore, academia - as it is such a key process in the manufacture of many solid ...

Small molecules, tablets, capsules, soft gels, effervescence, gummies, and pills. These are all oral solid dosage (OSD) forms, a term that refers to a final drug product therapy that is ingested ...

The last decade has seen an impressive growth in the research and mechanistic understanding of the agglomeration process, along with attempts to model the process. There have even been a few papers on ...