A low-fiber "Western diet" causes damage to the protective mucus barrier in the gut, and such damage can increase the risk of inflammation and infection. By studying the gut bacteria of people who ...

The terms "intestinal barrier" and "intestinal permeability" describe two different aspects of the same anatomical structure, the intestinal wall composed of four layers, the mucosa, the submucosa, ...

The colonic mucosal barrier is essential for maintaining digestive health, protecting against pathogens, and preventing inflammation. The Notch signaling pathway is implicated in these processes, as ...

Altered intestinal barrier function is postulated to be a central predisposing factor to intestinal diseases, including inflammatory bowel diseases and food allergies. However, the mechanisms involved ...

An international research team led by scientists from Bern and Charité - Universitätsmedizin Berlin has identified a previously unknown function of the intestinal nervous system. The study reveals ...

EVER since Réaumur, more than two centuries ago, discovered that gastric juice digests meat, men have asked: "Why doesn't the stomach digest itself?" There are two answers to this question. One is, of ...

The intestinal mucosa absorbs nutrients, water, and electrolytes in a controlled manner–while simultaneously keeping out toxins, allergens, and some bacteria. When this barrier is damaged, it is ...

-- The study presents the journey of designing and optimizing novel gut-restricted PHD inhibitors using the comprehensive generative chemistry engine Chemistry42. -- From initiation to preclinical ...

Patients who have undergone pelvic radiotherapy may live with low-grade chronic inflammation of the lower intestine 20 years after the treatment. This has been shown in a study by researchers at the ...

Dr. Umapathy Sundaram, known as Uma to colleagues, directs research efforts that translate molecular discoveries into ...