The neuromuscular junction - where nerves and muscle fibers meet - is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...

There are a number of disorders – both acquired and inherited – that interfere with the communication that occurs at the neuromuscular junction. For example, in Lambert-Eaton myasthenic syndrome, ...

Congenital myasthenic syndromes (CMSs) are a heterogeneous group of disorders that affect the safety margin of neuromuscular transmission — the depolarization that is required for propagation of the ...

Aarhus, Denmark, 25 March 2025 – NMD Pharma A/S, a clinical-stage biotech company dedicated to developing novel and improved treatments for patients living with neuromuscular diseases, today announces ...

ORLANDO, Fla.--(BUSINESS WIRE)--Hesperos, Inc. has increased its pioneering human-on-a-chip drug testing capabilities by adding a new in vitro, human-human neuromuscular model to its patented ...

Myasthenia gravis is an autoimmune disease in which antibodies bind to acetylcholine receptors or to functionally related molecules in the postsynaptic membrane at the neuromuscular junction. The ...

AbbVie Inc., Aquestive Therapeutics Inc, argenx SE, AstraZeneca Plc, Biogen Inc., CuraVac, F. Hoffmann La Roche Ltd., Grifols SA, Merck and Co. Inc., Nippon Shinyaku ...

We refer to a floppy infant as an infant with generalized hypotonia presenting at birth or in early life. There is a broad spectrum of underlying conditions, which can either be acquired or of genetic ...

The brain contains billions of nerve cells (i.e., neurons) which receive and integrate signals from the environment and govern the body's responses. This is made possible by synapses - contacts ...

A new, inherited neuromuscular disorder has been discovered by researchers. The rare condition is the result of a genetic mutation that interferes with the communication between nerves and muscles, ...