Immune signaling in IBD triggers tumor-promoting neutrophils which is linked to an increased risk of colorectal cancer.

This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the ...

Shi’s study, "Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling," was recently published in Nature Communications. “Concerted efforts ...

A new study published in the journal Science Signaling has found that an immune system protein plays a central role in the addictive mechanisms of methamphetamine. The findings suggest that tumor ...

Tumor Necrosis Factor-alpha (TNFα), a pivotal inflammatory cytokine, plays paradoxical roles in cancer—both promoting tumor survival and triggering cell death. A comprehensive review by Sonal M.