The colonic mucosal barrier is essential for maintaining digestive health, protecting against pathogens, and preventing inflammation. The Notch signaling pathway is implicated in these processes, as ...

Many biological processes exhibit daytime differences governed by rhythmic exposure to sunlight, termed circadian rhythms. Researchers at Penn State recently found, in mice, that a protein critical to ...

Altered intestinal barrier function is postulated to be a central predisposing factor to intestinal diseases, including inflammatory bowel diseases and food allergies. However, the mechanisms involved ...

An international research team led by scientists from Bern and Charité - Universitätsmedizin Berlin has identified a previously unknown function of the intestinal nervous system. The study reveals ...

Radhakrishna Rao, PhD, vice-chair and professor in the Department of Physiology at the University of Tennessee Health Science Center (UTHSC), has received two large national awards totaling $5 million ...

The food additive carrageenan (E 407) can be responsible for the development of chronic inflammatory bowel disease, ulcers, and increased blood sugar levels in animals. Researchers have now ...

From Ayurveda to the teachings of Hippocrates, medicine's earliest traditions advanced a belief that the gut was the foundation of all health and disease. It wasn't until recently, however, that ...

-- The study presents the journey of designing and optimizing novel gut-restricted PHD inhibitors using the comprehensive generative chemistry engine Chemistry42. -- From initiation to preclinical ...

Dr. Umapathy Sundaram, known as Uma to colleagues, directs research efforts that translate molecular discoveries into ...

A research team from Shenyang Agricultural University, led by Dr. Bin Li, has highlighted the potential of malvidin-3-O-galactoside (M3G), a blueberry-derived anthocyanin, to improve colonic mucosal ...